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🧬 MTHFR: The Genetic Key That Could Be Blocking Your Healing
By Dr. Steve Moretta
Advanced Functional Medicine | Emotional Integration | Cellular Regeneration
www.drstevemoretta.com
What if your chronic fatigue, hormone imbalance, or emotional struggles weren’t just circumstantial… but encoded in your DNA?
Welcome to the world of MTHFR, a gene that—when altered—can silently sabotage your body’s ability to detox, regenerate, and heal.
🔍 What Is MTHFR?
MTHFR stands for Methylenetetrahydrofolate Reductase, an enzyme your body needs to perform a critical process called methylation.
Methylation impacts:
- Detoxification of toxins, estrogens, and heavy metals
- DNA repair and gene regulation
- Energy production (ATP)
- Brain chemistry and emotional regulation
- Inflammation and cardiovascular health
If your MTHFR gene is mutated, your body may struggle to activate folate (vitamin B9) and detox effectively. This leads to a cascade of dysfunctions that can affect your hormones, your mind, and your immune system.
🧬 Common MTHFR Variants
The two most studied genetic variants are:
- C677T: Linked to high homocysteine levels, cardiovascular risk, and poor detox
- A1298C: Often affects neurotransmitter balance, mood, and mental clarity
- Compound heterozygous (both mutations): Carries a higher risk of methylation impairment and chronic illness
🧠 Symptoms You Might Notice
- Chronic fatigue or fibromyalgia
- Brain fog, anxiety, or depression
- Hormonal imbalances (PMS, PCOS, thyroid issues)
- Histamine intolerance or migraines
- Miscarriages or fertility challenges
- Poor response to medications or supplements
- Elevated homocysteine in lab work
🧬 Why MTHFR Matters in Functional Medicine
In my clinical practice, I’ve seen how MTHFR mutations intersect with chronic illness, emotional trauma, and environmental toxicity. These patients are often “the mystery cases”—they’ve tried everything, yet their bodies don’t respond.
The key?
It’s not just about treating symptoms. It’s about supporting your body’s unique genetic blueprint.
This is the heart of the Epigen-Q™ Method:
We don’t treat diseases. We restore the terrain—genetic, emotional, and biochemical—so the body can finally heal.
💊 What to Do If You Have an MTHFR Mutation
Fortunately, MTHFR is not a life sentence. With the right support, you can bypass the blocks and optimize your biology:
Functional Steps to Support Methylation:
- ✅ Use L-methylfolate (active folate) instead of folic acid
- ✅ Supplement with methyl-B12, B2, and magnesium
- ✅ Reduce exposure to toxins and estrogen disruptors
- ✅ Support liver function with glutathione, NAC, and herbal detoxifiers
- ✅ Avoid folic acid in fortified foods and cheap supplements
- ✅ Address emotional stress and trauma (key methylation disruptors)
- ✅ Test homocysteine and full methylation panel
🧠 Final Thought:
“Your genes are not your destiny—
but they are your signal.
Learn to listen, and you can take back control of your healing.”
If you suspect that your genetics may be holding you back, it’s time to get tested and build a protocol tailored to your biology, your emotions, and your purpose.
📍 Moretta Health & Wellness Centers
24285 Katy Freeway, Suite 300, Katy, TX, 77494
🌐 www.drstevemoretta.com
